Group Lead - Antibody–Oligo Conjugates (AOC)

Job Description Group Leader, Antibody–Oligo Conjugates (AOC) You are an experienced bioconjugation or AOC‑focused scientist who thrives in discovery. You know how to design, implement, and optimise antibody–oligo conjugates, build assays, validate constructs, and move programmes toward candidate selection. You want to lead a function, build a team, and shape an emerging therapeutic platform from the ground up. A newly established RNA‑therapeutics initiative is scaling rapidly and now seeks a Group Leader, Antibody–Oligo Conjugates to lead AOC engineering, bioconjugation workflows, assay development, and cross‑functional integration. The programme is expanding from 13 to 80 scientists and needs leaders who make things happen, build systems, and deliver progress at pace. THE ROLE You will lead the AOC engineering and bioconjugation strategy, implementing antibody‑based tissue‑targeting approaches while simultaneously building the team around you. Your work ensures that AOCs move efficiently from design → conjugation → assay → validation → pre‑candidate stage. This is a discovery‑heavy, hands‑on scientific leadership role where you define how the entire AOC workflow operates. KEY RESPONSIBILITIES Lead AOC engineering for tissue‑targeting applications, including design and implementation of conjugation strategies Build complete flow‑schemes for AOC discovery; from design through screening, validation, and selection Own bioconjugation strategy and oversee the work of a Bioconjugation Scientist/Senior Scientist Oversee antibody generation, CRO interactions, and characterisation of known binders Act as a scientific leader, problem‑solver, and good citizen within a multicultural, startup‑style team ABOUT YOU Strong background in bioconjugation, ADC/AOC engineering, or related antibody–nucleic acid modalities Deep experience developing assays, validating conjugates, and understanding toxicity vs non‑toxicity mechanisms Ability to run full discovery flow‑schemes and drive programmes toward candidate selection Built and managed teams. LOGISTICS Full‑time, on‑site in Singapore Visa sponsorship available Very competitive benefits structure; relocation support available Effective income tax typically 18–19% (max 24%) Competitive Annual Salary If you want to build a next‑generation AOC platform inside a rapidly scaling discovery organisation, Apply now!