Postdoctoral Training Fellow
The Institute of Cancer Research
United Kingdom
Research and Science
Job posted on May 12, 2025
APPLY NOW
Job Description:
Key Information
Salary: Dependent on relevant Postdoctoral experience.
This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here .
Duration of Contract: Fixed Term for 3 years
Hours per week: 35 hours per week (Full Time)
Location: Chelsea
Closing Date: 1 June 2025
Job Details
Under the guidance of Professor Alan Melcher , we are seeking a creative and motivated Postdoctoral training Fellow to study ways to improve CAR-T cell therapy for breast cancer. We will use radiotherapy to enhance CAR-T cell access to solid breast tumour models in vivo and oncolytic viruses (OV) to improve anti-tumour functionality, including via the generation of ‘dual-specific CAR-T’, which target both the tumour-associated antigen, through their CAR, and the OV (eg reovirus, herpes simplex virus), through their own, endogenous TCR.
About You
The successful candidate must have a PhD in a biological science combined with a knowledge of cancer biology and cancer immunology. Experience in cell culture techniques and pre clinical immunology in-vivo models is essential.
Candidates who are nearing completion of their PhD may apply, but confirmation on awarded PhD is required within 6 months of employment.
The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 7 years.
For general information on Postdocs at The ICR, more information can be found here .
Department/Directorate Information
The Breast Cancer Immunology team is led by Alan Melcher and looks at ways to activate the immune system to attack breast cancer using therapeutic oncolytic viruses, vaccines, radiotherapy, targeted drugs and combination strategies.
The Breast Cancer Immunology team is part of the Breast Cancer Now Toby Robins Research Centre, within the Division of Breast Cancer Research at the ICR. The Centre is the first centre in the UK entirely devoted to breast cancer research. Our goal is to advance research into the causes, diagnosis and treatment of breast cancer. It is located in state-of-the-art laboratory space, with excellent core facilities and is funded through a long term renewable programme grant from Breast Cancer Now.
What We Offer
We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Alan Melcher by emailing [email protected]
About The Institute Of Cancer Research
Why work for us?
As a member of staff, you'll have exclusive access to a range of staff benefits .
The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.
The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here .
At the Institute of Cancer Research, we champion diversity as we believe it fuels innovation and drives impactful research. We welcome applicants from all walks of life, valuing diverse perspectives that enrich our work.
Don't let a checklist of qualifications hold you back – if you're passionate about the role, we want to hear from you. Your unique experiences and backgrounds contribute to the richness of our team. We are committed to being an equal opportunity for all, regardless of ethnicity, gender, age, sexual orientation, disability, or any other dimension of diversity. Join us in creating an inclusive environment where everyone's voice is heard and valued.
APPLY NOW
Salary: Dependent on relevant Postdoctoral experience.
This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here .
Duration of Contract: Fixed Term for 3 years
Hours per week: 35 hours per week (Full Time)
Location: Chelsea
Closing Date: 1 June 2025
Job Details
Under the guidance of Professor Alan Melcher , we are seeking a creative and motivated Postdoctoral training Fellow to study ways to improve CAR-T cell therapy for breast cancer. We will use radiotherapy to enhance CAR-T cell access to solid breast tumour models in vivo and oncolytic viruses (OV) to improve anti-tumour functionality, including via the generation of ‘dual-specific CAR-T’, which target both the tumour-associated antigen, through their CAR, and the OV (eg reovirus, herpes simplex virus), through their own, endogenous TCR.
About You
The successful candidate must have a PhD in a biological science combined with a knowledge of cancer biology and cancer immunology. Experience in cell culture techniques and pre clinical immunology in-vivo models is essential.
Candidates who are nearing completion of their PhD may apply, but confirmation on awarded PhD is required within 6 months of employment.
The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 7 years.
For general information on Postdocs at The ICR, more information can be found here .
Department/Directorate Information
The Breast Cancer Immunology team is led by Alan Melcher and looks at ways to activate the immune system to attack breast cancer using therapeutic oncolytic viruses, vaccines, radiotherapy, targeted drugs and combination strategies.
The Breast Cancer Immunology team is part of the Breast Cancer Now Toby Robins Research Centre, within the Division of Breast Cancer Research at the ICR. The Centre is the first centre in the UK entirely devoted to breast cancer research. Our goal is to advance research into the causes, diagnosis and treatment of breast cancer. It is located in state-of-the-art laboratory space, with excellent core facilities and is funded through a long term renewable programme grant from Breast Cancer Now.
What We Offer
- A dynamic and supportive research environment
- Access to state-of-the-art facilities and professional development opportunities
- Collaboration with leading researchers in the field
- Competitive salary and pension
We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Professor Alan Melcher by emailing [email protected]
About The Institute Of Cancer Research
Why work for us?
As a member of staff, you'll have exclusive access to a range of staff benefits .
The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.
The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here .
At the Institute of Cancer Research, we champion diversity as we believe it fuels innovation and drives impactful research. We welcome applicants from all walks of life, valuing diverse perspectives that enrich our work.
Don't let a checklist of qualifications hold you back – if you're passionate about the role, we want to hear from you. Your unique experiences and backgrounds contribute to the richness of our team. We are committed to being an equal opportunity for all, regardless of ethnicity, gender, age, sexual orientation, disability, or any other dimension of diversity. Join us in creating an inclusive environment where everyone's voice is heard and valued.