Clinical Research Fellow

About us The main focus of the Department of Neuroinflammation is research into multiple sclerosis (MS), and we employ a broad range of basic and clinical methods, including clinical therapeutic trials. The Optimal Clinical Trials Platform for Progressive Multiple Sclerosis (OCTOPUS) is a multi-arm, multi-stage (MAMS) adaptive platform trial designed to accelerate the development of re-purposed or novel treatments aimed at slowing or halting disability progression. The trial is being conducted at neuroscience sites across the UK, including the Queen Square MS Centre (QSMSC). Treatments tested within the platform will primarily target the mechanisms of neuroprotection and remyelination. About the role We are seeking a Clinical Research Fellow to work on all clinical aspects of the OCTOPUS project, led by Professor Jeremy Chataway (UCL, Chief Investigator) and Professor Max Parmar (Director, MRC CTU, UCL). You will work closely with Professor Chataway and the UCL MRC CTU team on the daily operations of the trial. Responsibilities include contributing to the UK-wide recruitment strategy, pre-screening participants from the OCTOPUS expression of interest portal, recruiting and consenting patients at UCLH, conducting clinical assessments, and collaborating on data collection, processing, and interpretation. You will also coordinate blood collection and analysis and participate in broader data analysis activities. As part of the post's academic nature, you will be expected to contribute to ongoing and new research projects and will have the opportunity to be involved in both acute and long-term care of people with MS. You will have the option to enrol as a doctoral student and complete a PhD alongside employment. An honorary contract will be sought from UCLH NHS Foundation Trust (and any other Trusts where the postholder may provide input), for which a DBS check will be required. The post is available from 01 August 2026 and is funded by OCTOPUS until 31 December 2028 in the first instance. If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact the Institute of Neurology HR Team (email is in the Job Description). Informal enquiries regarding the role can be addressed to Dr Sean Apap Mangion and Dr Charles Wade (emails are in the Job Description). For a full job description and to apply for this role please visit UCL's online recruitment portal (https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs) and search using vacancy reference B02-08865. About you You will be a registered Medical Practitioner, licensed to practise in the UK, and have completed CMT/IMT training and MRCP. You should have an understanding of the biology of neurological conditions and/or assessments and of research methodology, with evidence of effective research carried out under direction, and be capable of providing clinical supervision. Excellent communication, interpersonal, and organisational skills, along with the ability to work independently and act on your own initiative, are essential for this role. This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa. What we offer The role is offered with salary in the range of £48,580 - £75,038 per annum including London Allowance, on the CL, RDPS, or StR scale, dependent on NHS contract and/or stage of clinical training. As well as the exciting opportunities this role presents, we also offer great benefits; visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more. This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit https://www.ucl.ac.uk/human-resources/conditions-service-research-teaching-and-professional-services-staff for more information. Our commitment to Equality, Diversity and Inclusion As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. 12% of Institute staff are actively working on EDI initiatives; visit https://www.ucl.ac.uk/ion/equality-diversity-inclusion for more information about what we're doing. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce; these include people from Black, Asian and ethnic minority backgrounds, disabled people, LGBTQI+ and gender diverse people in all roles, and women in Grade 9 and 10 roles.